Heart of the Oak, Chains of Honor and Sanctuary are a combination of Rune Words that I use on most of my Casters. I strongly recommend this Rune Word for any Casters who need a good weapon. No matter what class you are this weapon will be useful to you as a Caster. Without a doubt this is the best universal caster Rune Word in the game. Extra tip: Use an Ethereal Polearm as it can't break when your Mercenary is using it, you'll be able to boost his damage this way!

When put into a Polearm and equipped onto an Act 2 Mercenary you'll share the Meditation Aura with him.

The reason for this is because Insight comes with Meditation Aura which gives you insanely good mana regeneration. This weapon makes every Rune Word list whether it be beginner, intermediate or the best Rune Words in the game. Level 12-17 Meditation Aura When Equipped (varies) Prior to the Monarch shield there are not many shields with 4 Sockets. Despite this being a level 25 Rune Word you can't typically use it until level 54+ when your character can equip a Monarch shield. There are plenty of better Rune Words that you can use for a weapon but Spirit offers you +2 to Skills on a shield which is very rare. Specifically the Spirit Shield Rune Word is the one that is 'the best'. Every Rune Word on this list is meant for characters who are level 50+, if you'd like to check out my other lists of Rune Words then follow the links below.

This page contains a list of all the best Rune Words in Diablo 2 as well as a little bit of information about why they're on this list to begin with.

Rune diablo 2 list